Connect with us

Headlines

Chinese, U.S. scientists propose drug delivery tools for brain cancer

Published

on

Chinese and U.S. scientists have proposed a new drug delivery system that can improve immune therapy treatment for brain cancer.

The researchers from Shandong University and the University of Wisconsin-Madison designed an injectable hydrogel that contains nanoparticles targeting the glioma stem cells.

Glioma stem cells are known to be the main culprits for the recurrence of glioblastoma, a highly invasive tumour in the brain, after surgical removal of the initial tumour.

Advertisement

Nanoparticles within the proposed hydrogel can create chimeric antigen receptor (CAR) macrophages in situ after being injected into the resection cavity.

According to the study published this week in the journal Science Translational Medicine, the macrophage is a large cell that can remove harmful substances from the body and is found in blood and tissue.

Such modified macrophages can seek and engulf residual glioma stem cells in the cavity by stimulating an adaptive antitumor immune response, according to the study.

Advertisement

In a preclinical humanised mouse model, the drug delivery system was shown to prevent post-operative glioma relapse by inducing long-term antitumor immunity in mice.

Also, in combination with an antibody called CD47, the hydrogel increased the frequency of positive immune responding cells in rodents, according to the study.

The work offers a potential treatment strategy for priming cancer stem cell-specific immunity with broad application in patients suffering from recurrent malignancies and warrants further clinical study.

Advertisement

Prof. Jiang Xinyi, of the Shandong University, said in the paper’s co-corresponding author.

(Xinhua/NAN)

Advertisement
Continue Reading
Advertisement
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Headlines

Tinubu arrives Katsina to receive Buhari’s body for burial

Published

on

President Bola Tinubu, on Tuesday arrived in Katsina to receive the remains of the former President Muhammadu Buhari, who passed away in London on Sunday at the age of 82.

The News Agency of Nigeria (NAN) recalls that Vice-President Kashim Shettima departed London in the early hours of Tuesday with the remains of Buhari back to Nigeria.
On arrival at the Umaru Musa Yar’adua Airport Katsina, Tinubu was received by Gov. Dikko Radda,  former Vice-President Yemi Osinbajo, governors, Chairman of Dangote Group, Alhaji Aliko Dangote, Deputy Senate President, Jibrin Barau, and Speaker of the House of Representatives,  Tajudeen Abbas.
Others are Ministers, former governors, former and serving Senators, Alhaji Dahiru Managl,  former Minister of Information and Culture, Lai Mohammed, members of the All Progressives Congress (APC) National Working Committee (NEC), amongst others.
Continue Reading

Headlines

“He Never Turned His Back on the Needy” — Tributes Pour In Ahead of Buhari’s Burial

Published

on

Just hours before the burial of former President Muhammadu Buhari, heartfelt tributes have continued to pour in from beneficiaries of his many charitable deeds, with many describing him as a man who never turned his back on the needy.

Speaking to the News Agency of Nigeria (NAN) on Tuesday, Aminu Daura, a respected community elder, recalled how Buhari consistently provided foodstuffs during Ramadan for families, friends, widows, and orphans in his hometown.

“He never made noise about it, but many homes had food on their tables during fasting period because of him,” Daura said.

Advertisement

Abdullahi Sani, a physically-challenged man who received a tricycle from the Buhari Foundation in 2021, was overcome with emotion while speaking to NAN.

“I can move around and feed my family today because of Baba Buhari. I pray to Allah to reward him for giving hope to people like me,” he said, in tears.

Hajiya Fatima Yahaya, another resident, remembered Buhari’s acts of kindness during festive seasons.

Advertisement

“Even after he left office, his aides ensured that the usual support still reached us every year. He always remember his people,” she said, referring to his distribution of Sallah rams and food items to indigent families during Eid celebrations.

Other residents of Daura also shared memories of how the late former president quietly paid school fees and medical bills for struggling families, actions rarely publicized.

“Some of us benefited from his silent interventions. He was a true father and a great figure in the society,” said Ali Saidu.

Advertisement

On Monday night, Imams across various mosques in Daura held special Qur’anic recitations, praying for the forgiveness of Buhari’s sins and his eternal peace.

The Chief Imam of Daura Central Mosque, Sheikh Musa Kofar Barau, described Buhari as a humble leader whose legacy of service and compassion would remain alive in the hearts of the people.

Buhari is scheduled to be buried later on Tuesday in his hometown of Daura, Katsina State, in line with Islamic rites. The community is bracing to welcome thousands of mourners from across Nigeria and beyond.

Advertisement
Continue Reading

Headlines

King Mohammed VI Mourns Buhari, Praises Legacy of Nigeria’s Former Leader

Published

on

His Majesty King Mohammed VI of Morocco has extended heartfelt condolences to President Bola Tinubu, the family of the late former President Muhammadu Buhari, and the entire Nigerian people following Buhari’s death.

In a message of sympathy, the Moroccan monarch described the passing of the former Nigerian leader as a “sad occurrence,” expressing deep sorrow over the loss.

King Mohammed VI hailed Buhari as “an illustrious leader who worked untiringly to serve his country’s best interests and lead his people toward further progress and prosperity.”

Advertisement

He added: “Our thoughts and prayers are with you and the bereaved. I share your grief and want you to know how much I appreciated the working sessions I had with the deceased.”

Reflecting on their bilateral engagements, the king noted that his collaboration with Buhari led to the launch of promising development projects, “ushering a new era grounded in friendship and close cooperation between our two sister nations.”

Advertisement
Continue Reading

You May Like

Copyright © 2025 Acces News Magazine - All Right Reserved.

Verified by MonsterInsights